Update Your USP Methods with Metrohm Ion Chromatography

The United States Pharmacopeia (USP) has updated and modernized all its current monographs to include Ion Chromatography (IC) methods for the analysis of pharmaceutical assays, impurities and excipients. IC is a flexible, easy-to-use and robust, multi-parameter analytical technique suitable for the determination of anions, cations and other types of charged molecules. Metrohm has partnered with USP to develop Ion Chromatography methods and provides robust solutions for your standard pharmaceutical analyses. Metrohm Ion Chromatography (IC) systems are ideal solutions for pharmaceutical testing of active pharmaceutical ingredients (APIs), impurities and excipients, and are fully compliant with USP General Chapters such as: • <1225> Validation of Compendial Procedures • <621> Chromatography • <1065> Ion Chromatography • <191> Identification Tests – General • <345> Assay for Citric Acid/Citrate and Phosphate • <591> Zinc determination Compared to single-parameter methods such as titration, ion measurement and other wet chemical procedures, Ion Chromatography: More efficient: Multiple parameters can be determined in a single run More selective: Target analytes can be clearly identified Safer: Hazardous procedures and materials such as solvents, reagents and other chemicals are not required. Metrohm has been developing and manufacturing Ion Chromatography systems for over 30 years. What Metrohm Ion Chromatography means:

• Robust systems: We provide 3 years warranty for our Swiss-made instruments and 10 years warranty for our anion suppressor units.
• Compatibility: Metrohm IC systems can be controlled with our MagIC Net software or options such as OpenLab CDS (Agilent) and Empower^TM CDS (Waters^TM).
• Compliance: Metrohm IC instruments are GLP-compliant and meet all requirements regarding data integrity, security and traceability in accordance with FDA 21 CFR Part 11, ALCOA and ALCOA+.
• Professional service and support: Metrohm provides local service through subsidiaries in over 40 countries, including Turkey, and authorized representatives in more than 40 countries.

Watch our video to learn about Metrohm IC: https://www.youtube.com/watch?v=Mw7Bt5jq-5g&ab_channel=MetrohmTV For detailed information on pharmaceutical monographs, analyses and impurity assessments, visit our Turkish website: https://www.metrohm.com/tr_tr/products/ion-chromatography/usp-monographs-using-ion-chromatography.html Best regards, Metrohm Turkey Academy Team