Immedeline PG-GL: Instant Botox Effect Active Ingredient
The fight against the natural effects of aging has always been the focus of beauty industry consumers.
In addition to long-term solutions, consumers are increasing their interest in products that can see their effects more quickly and instantly.
According to the studies, 95% of anti-aging product advertisements appear as “firming”, and we see that the concept of “firming” has taken over the popularity of the concept of “anti aging”.
At this point, Immedeline PG-GL, the active ingredient developed by Shanghai JAKA Biotech, which acts against wrinkles and instant tightening, comes out with the qualities that can meet the needs of consumers.
The Immedeline PG-GL is obtained from very special peach gum called as snow peach that grows in Jade Dragon Snow Mountain which has the unique enviromental factors provide the excellent conditions for growth of peach gum.
Peach gum is secreted from the wounds formed by the bark of peach trees under the
influence of external forces and this gum has the potential to tighten even cracked bark. Peach gum polysaccharides with specific molecular weight interval combination can achieve the best skin tightening effect.
Features & Benefits
Immedeline PG-GL is a natural biopolymer that can bring instant tightening and lifting effect to skin. It brings to the skin visible tightening and lifting effects: tightening can be felt in 5 minutes and obvious wrinkles reduction could be observed in 10 minutes.
At the end of 2 hours, maximum tightening is observed and the effect lasts for 8 hours. The threedimensional film formed by Immedeline PG-GL can effectively make wrinkles invisible.
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1) Anti Wrinkle Data[/caption]
In Vivo Test (Wrinkle Visibility);
• Test area : corners of eyes of a healthy person (n=12)
• Method:
◊ Apply a base gel containing 5% Immedeline PG-GL on the corners of the eyes;
◊ Take pictures with VC98 and VISIA after different time;
◊ Data analysis and processing, SEr skin roughness parameter; SEw skin wrinkle parameter.

In Vivo test results show that Immedeline PG- GL ;
• Increases the skin smoothness more than % 30 in 5 minutes.
• Decreases the appearance ow wrinkles more approximately 15% in 5 minutes.
• Minimizes the appearance of wrinkles after 2 hours.
• Wrinkle removal effect lasts for 8 hours.
2) Skin Firming Data
In Vivo Test
Test Area: Corners of eyes of a healthy persons(n=25)
• Method:
◊ Apply products containing 2%, 5% and 10% Immedeline PG-GL.
◊ Absorb and dry at room temperature.
◊ Subjectively evaluate whether there is skin firmness or on which side skin firmness is
more obvious.
In Vivo test results show that Immedeline PG- GL ;
• 2% Immedeline PG-GL already has obvious skin firming effect.
• 5%, 10% Immedeline PG-GL produce better skin firmness.
In Vivo Test (Skin Elasticity)
• Test Area: Cheekbones of a healthy person (n=6)
• Method:
◊ Apply a base gel containing 10% Immedeline PG-GL.
◊ Detect skin elasticity with MPA580 at different time points.
◊ Calculate skin elasticity growth rate and analyze statistical differences (R2).
In Vivo test results show that Immedeline PG- GL ;
• After 5 min skin elasticity increses as 16,9%
• After 2 hours, skin elasticity is the best.
• Elasticity increases continuously for 8 hours.
3) Moisturizing Data
In Vivo Test (Skin Moisture)
• Test Area: Arms of healthy person (n=15)
• Method:
◊ Prepare a sample is a 2% aqueous solution of ImmedelinePG-GL.
◊ Detect skin moisture content and TEWL respectively with CM825 and TM300 at 1h, 3h
and 6h after application.
◊ Calculate the change rate of skin moisture related
parameters and analyze statistical differences.

2% Immedeline PG-GL can enhance the moisturizing power of skin.

Applications Immedeline PG-GL can be used in tightening, lifting and instant antiwrinkle products on eye corners, forehead, cheeks, etc.
It has excellent water solubility and is suitable for various formulations such as lotions, essences, gels, creams (face,eye ,neck, etc..) and face masks.
You will definitely want to add this versatile active ingredient, which has a consumer-saving role in all different scenarios (such as dating, meeting, performance…) where an instant firming effect is needed, to your skin care routine.
For detailed information, we will be pleased to welcome you at our booth at the CHCI Exhibiton, which will take place between 31 May – 2 June 2023. (Hall 9, Booth No: A 510)
Merve Dedeoğlu
Technical Sales Manager
Ravago Chemicals Turkey