VITAMK7®, NEW PERSPECTIVES FOR FERMENTED VITAMIN K2 AS MK7
Nowadays Vitamin K2 as menaquinone-7 (MK7) is one of the more appealing ingredient in the human health and the market is expected to grow with a CAGR of roughly 24.7% over the next five years and will reach 270 million US$ in 2024, from 73 million US$ in 2019, according to a new GIR (Global Info Research) study.
The importance of Vitamin K2 in human well-being is today widely recognized: numerous clinical evidences demonstrate a key role in bone and heart health while new vital roles are going to be elucidated.
Vitamin K2 in the form of menaquinone-7 (MK7) is essential for calcium utilization, helping build strong bones and inhibit arterial calcification. MK7 was isolated for the first time from natto, a traditional Japanese food obtained from the fermentation of beans with the Bacillus subtilis natto bacterium.
Natto food has a history of dietary consumption dating back at least 1,000 years ago. Gnosis by Lesaffre is today leader in Vitamin K2 obtained by fermentation of B. subtilis natto under the brand name of vitaMK7®.
With more than 10 years of manufacturing, the company is the sole European producer of Vitamin K2 as MK7, without intermediaries or brokers. The production process is carried out in it is own approved cGMP plant in compliance with the strictest quality rules, ISO and HACCP quality systems.
The entire supply chain is constantly monitored and conducted with full transparency: Gnosis by Lesaffre offers the opportunity to control every step of the manufacturing process of the vitaMK7® products by it is customers, to enable to understand the rules applied and how the company can guarantee pure, stable, safe, high quality
source of Vitamin K2 as MK7. VitaMK7® has also KOSHER and HALAL certifications. VitaMK7® also offers “Clean label”, a recognizable value by the global market.
It derives from the biofermentation of a highly purified natural microbial strain grown under strictly controlled conditions. The patented fermentation production of vitaMK7® employs the Bacillus subtilis natto, following what happens in the natural environment during the production of the Japanese natto food.
The very pure profile is achieved without chemicals and synthetics as well as the very high content of the all-trans active isomer (higher than 99%). Thanks to it is clean profile, VitaMK7® minimizes cross-reactions with other ingredients, and ensures greater effectiveness and stability in formulations.
New Application Trend
A very promising and emerging sector of vitamin K2 as MK7 is related to fortified milk and dairy products: even though milk does not contain the MK7, the fats contained in it are an ideal food matrix and carriers for lipophilic vitamins like MK7.
Dairy products have a relevant lipid components that ranges from 1-2% of skimmed milk to 9% in some fat concentrated yogurt. Fortified milk is widely used around the world to help people get nutrients that may otherwise be lacking in their diets.
Examples are vitamin D, Vitamin A, Vitamin B9 (folate), minerals and micronutrients. Findings arrive from a recent publication appeared in Nutrafoods Journal where serum Vitamin K levels in healthy subjects were compared after a single oral administration (1 mg) of Gnosis by Lesaffre vitaMK7® diluted in 1%-fat milk either as a powder or as a pre-emulsified dispersion (oil–water emulsion).
Even if both formulations increased serum MK7 levels in all subjects, the results highlighted that, there is a highly significant difference for the emulsified vitamin formula with highly significant increase in the bioavailability of MK7 over the 8 hours.
Fortification of dairy products with MK7 completes the “perfect combo” for bone health (Ca++, Vit D and Vit K2), in an easy-to-use and highly bioavailable manner. For information visit Gnosis by Lesaffre and the dedicated website of vitaMK7®. Contact us during Food & Nutritional Ingredients Exhibition at Arısan Group Booth Hall 9 Stand 860.
Dr. Lorena Carboni - Bilimsel Danışman / Scientific Advisor - Gnosis
