Cutaneous Blesmishes, the Answer Already Lies on Your Skin: EPS Seapur

1 in 3 women aged 25 to 40 say they are affected by the regular appearance of acne-type lesions. Besides acne, cutaneous blemishes reflect a reduction in anti-microbial protection and imbalance in the cutaneous microbiota. Rather than developing compounds targeting the agents responsible for these inflammatory lesions, our laboratories decided to work in partnership with the resident flora of the skin.

What is a Postbiotic?

A postbiotic is a compound produced by bacteria which can take care of the bacterial ecosystem. Why marine product? Because bacterioplankton and human microbiota are 73% similar. Cutaneous blemishes are an inflammatory response to stress. A period of temporary stress causes an imbalance in the cutaneous microbiota, which leads to inflammatory reactions.

Cutaneous blemishes develop more quickly on a cutaneous barrier which has been altered. Daily exposure to external aggressions as well as ageing is accompanied by weakening of the cutaneous barrier, which plays a role in both physical and microbial protection.

The 3 genus the most represented on the surface of the skin are Propionobacteria, Corynebacteria and Staphylococci. Inside this ecosystem, Staphylococcus epidermidis and Propionobacterium acnes interact continually. S. epidermidis has the ability to control the proliferation of P. acnes to maintain microbiota balance and the healty of the skin. After 28 days of twice daily applications by a group of 30 volunteers with moderate lesions; EPS SEAPUR, acts for the cutaneous microbiota and promotes self-rebalancing. EPS SEAPUR; re-adjusts the ratio between S.epidermidis / P.acnes by +13%. This result indicates activity that promotes S. epidermidis. Given it is ability to control the growth of P. acnes this result should be accompanied by a reduction in the number of lesions. EPS SEAPUR, reduces inflammation induced by bacterial stress. EPS SEAPUR; decreases the release of IL8 by -30%. In addition to promoting the development of acneic lesions, an imbalance in the S. epidermidis / P. acnes ratio in favour of P. acnes also leads to release of IL8. EPS SEAPUR rebalances the S. epidermidis /P. acnes ratio and reduces the production of IL8. EPS SEAPUR, increases the synthesis of LCE3C. EPS SEAPUR; stimulates the synthesis of LCE3C by +52%. LCE (Late Cornified Envelope) proteins have two major functions for protecting the skin: they are part of the composition of the corneal envelope and therefore of the barrier function; they have anti-microbial properties (innate immunity) to prevent the development of opportunistic bacteria. Our laboratories have shown that LCE3C is decreased in stressed skin models and old skin models.

EPS SEAPUR, reduces the number and redness of lesions. EPS SEAPUR, improves the quality of the skin.

Visualisation of changes to a papule using C-Cube technology;

  Nevin Ormancı Chemist Arerko Kimya Sanayi ve Ticaret A.Ş.