Cutaneous blemishes are an inflammatory response to stress. A period of temporary stress causes an imbalance in the cutaneous microbiota, which leads to inflammatory reactions.
After 28 days of twice daily applications by a group of 30 volunteers with moderate lesions; EPS SEAPUR, acts for the cutaneous microbiota and promotes self-rebalancing.
EPS SEAPUR; re-adjusts the ratio between S.epidermidis / P.acnes by +13%. This result indicates activity that promotes S. epidermidis. Given it is ability to control the growth of P. acnes this result should be accompanied by a reduction in the number of lesions.
EPS SEAPUR, reduces inflammation induced by bacterial stress.
EPS SEAPUR; decreases the release of IL8 by -30%. In addition to promoting the development of acneic lesions, an imbalance in the S. epidermidis / P. acnes ratio in favour of P. acnes also leads to release of IL8. EPS SEAPUR rebalances the S. epidermidis /P. acnes ratio and reduces the production of IL8.
EPS SEAPUR, increases the synthesis of LCE3C.
EPS SEAPUR; stimulates the synthesis of LCE3C by +52%. LCE (Late Cornified Envelope) proteins have two major functions for protecting the skin: they are part of the composition of the corneal envelope and therefore of the barrier function; they have anti-microbial properties (innate immunity) to prevent the development of opportunistic bacteria. Our laboratories have shown that LCE3C is decreased in stressed skin models and old skin models.
EPS SEAPUR, reduces the number and redness of lesions. EPS SEAPUR, improves the quality of the skin.
Visualisation of changes to a papule using C-Cube technology;
Nevin Ormancı
Chemist
Arerko Kimya Sanayi ve Ticaret A.Ş.
